赌博可是一件很危险的事情，一不小心就或许会倾家荡产，失去所有。表达lose ones shirt 失去衬衣非常形象地形容了一个人因为赌博或在高风险投资项目中失败而输掉所有些财产，包含自己穿的衬衣，变得一无所有。
例句
I lost my shirt on a bad investment. I didnt realise that it was a scam.
I dont want to go to Las Vegas. Im worried Id lose my shirt in the casinos.
If you dont know what youre doing its very easy to lose your shirt on the stock market.
请注意
另一个和衬衣有关的表达是keep your shirt on 穿着你的衬衣。这个表达的实质含义是劝说某人要维持冷静，在对状况知道一些之前不要激动或生气。
例句
Alright, keep your shirt on! I said I was sorry I was late.
Keep your shirt on. No need to get angry. I am going to do the washing, I just need to finish my magazine first.